SPACE - Tiny Company Delivers Low-Cost Space Station Research

"The Space Station Is The Final Frontier Of Biological Research" by Alex Knapp, Forbes 2/13/2013

The frontier of biomedical research is inside an unassuming green box with a black-and-white touchscreen mounted on a rack in the International Space Station.  Within that green box is a microplate reader, a workhorse appliance in labs on Earth but the first of its kind to work in the near-zero gravity at 250 miles up.  A microplate reader screens hundreds of liquid samples at once for drug candidates or infectious disease, but fluids at zero Gs can float around or settle in unwanted ways.  This barred scientists from using microplates in space, where researchers prize the absence of gravity for its insights into how crystals, bacteria and drug agents behave.

Solving that problem was one small step for a tiny company called NanoRacks, which has carved out an unusual niche (and a monopoly, for now) adapting lab gear to the U.S. National Lab on the ISS.  Since 2010 it has designed and built all 36 of the modular labs there.  It has also acquired for the ISS two microscopes and a centrifuge that can simulate the gravity on, say, the moon or Mars. NanoRacks has flown 70 payloads to the ISS and is contracted to fly 80 more.  Last year it generated more than $3 million in revenue, of which only one-quarter comes from NASA.  Other customers include European and Saudi space agencies, universities in the U.K. and Vietnam, and even Scotch distiller Ardbeg, which sent up flavor molecules called terpenes to age for two years in charred oak (more on that experiment here).

NanoRacks’ entrepreneurial approach has cut the cost of doing science in space just as Elon Musk’s SpaceX has shown that startups can deliver payloads safely and more cheaply than governments can.  NASA told NanoRacks that a space-ready microplate reader would take years and cost millions.  “We told them we could do it in six months for less than a million,” says NanoRacks managing director Jeffrey Manber.  NanoRacks ended up doing it for $500,000 and even gave NASA the same money-back guarantee it offers commercial customers.  “We’ve only done that one other time,” says Marybeth Edeen, who manages the U.S. National Lab aboard the space station.  “It’s a good model in that incentivizes companies to build robust hardware.”

To make its microplate reader space-ready, NanoRacks had to tweak the capillary action of its 96 tiny wells to ensure that liquids were placed correctly on a slide and had to dumb down the machine’s user interface so an untrained astronaut could use it.  “When astronaut Kevin Ford turned it on and ran the initial experiment, we had to wait for it to run overnight,” says Manber.  “We had trouble sleeping. But in the morning we downloaded the data, and it was perfect.”

NanoRacks charges roughly $60,000 for each microplate reader experiment and is getting a lot more new customers beyond NASA, so it shouldn’t take the company too long to get a return on its investment.  “We were profitable last year, and we’ll be profitable this year,” says Richard Pournelle, NanoRacks’ senior vice president for business development.

Here’s a video showing the installation of the microplate reader on board the Station with some more information about Nanoracks.